ea0070aep539 | Endocrine-related Cancer | ECE2020
Montero-Hidalgo Antonio J.
, Jiménez-Vacas Juan M.
, Herrero-Aguayo Vicente
, Sarmento-Cabral André
, López Miguel
, Castaño Justo P
, Gahete Manuel D
, Luque Raúl M
Metformin has recently emerged as a potential therapeutic tool for different tumour pathologies, including prostate cancer (PCa)1, one of the leading causes of cancer-deaths in men worldwide. However, the molecular mechanisms underlying the antitumor effects of metformin in PCa are not fully elucidated. In this context, previous reports have suggested a relationship between metformin and the process of alternative splicing in some cell-types. Nevertheless, the poten...